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Fig. 2 | Molecular Medicine

Fig. 2

From: Visualisation of HER2 homodimers in single cells from HER2 overexpressing primary formalin fixed paraffin embedded tumour tissue

Fig. 2

Schematic representation of the sample preparation method. a Retrieval of a single cell suspension from an FFPE tumour block. The tumour block is first sectioned. The tumour is then macro-dissected and transferred into a tube for single cell retrieval by collagenase and dispase digestion. b HER2 membrane proteins are specifically labelled with Affibody peptides. The cells are then immobilized on a microchip, and streptavidin Quantum Dot (Strept.-QD) is attached. The final step is the coverage of the sample with a graphene sheet

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Molecular Medicine

ISSN: 1528-3658