Fig. 5
High magnification STEM images (80,000 x) from neighbouring regions on the same cell differing in their content of HER2 homodimers. a The image shows a total of 4362 detected particles with a density of 823 particles/μm2. b A similar image, recorded only a few microns away from the first image, and with a similar number of labels and label density value (3567 detected particles and 680 particles/μm2). c The g(r) analysis corresponding to A has no peak and thus indicates a lack of HER2 homodimers in this membrane region. d The g(r) for image b reveals a 20-nm peak indicating the presence of HER2 homodimers. Scale bars in a and b: 500 nm