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Fig. 5 | Molecular Medicine

Fig. 5

From: Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

Fig. 5

Comparative analysis of collagen III (a), fibronectin (b), and fibrotic markers in the peritoneal membrane as TGF-β (c) and FSP-1 (d) of all groups. mRNA levels were measured by quantitative real-time PCR (qRT-PCR). TAM and rBMP7 modulated the mRNA expression of all pro-fibrotic markers. Overall ANOVA p < 0.0001. Post-test p-values: *p < 0.01 vs Control; #p < 0.01 vs CKD, †p < 0.01 vs PF, §p < 0.01 vs PF/CKD, ϕp < 0.01 vs PF/CKD + TAM

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Molecular Medicine

ISSN: 1528-3658