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Fig. 9 | Molecular Medicine

Fig. 9

From: Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

Fig. 9

Immunohistochemistry for proliferative cell activity (PCNA) in the peritoneal membrane of the different groups (× 200). No significant proliferative activity was detected in the Control (a) or CKD groups (b). Peritoneal fibrosis induction promoted increased PCNA expression in the PF (c) and CKD/PF (d) groups. The groups treated with TAM (e) or rBMP7 (f) exhibited significantly reduced PCNA expression (g). Overall ANOVA p < 0.0001. Post-test p-values: *p < 0.01 vs Control; #p < 0.01 vs CKD, †p < 0.01 vs PF, §p < 0.01 vs PF/CKD

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Molecular Medicine

ISSN: 1528-3658