Fig. 9

Immunohistochemistry for proliferative cell activity (PCNA) in the peritoneal membrane of the different groups (× 200). No significant proliferative activity was detected in the Control (a) or CKD groups (b). Peritoneal fibrosis induction promoted increased PCNA expression in the PF (c) and CKD/PF (d) groups. The groups treated with TAM (e) or rBMP7 (f) exhibited significantly reduced PCNA expression (g). Overall ANOVA p < 0.0001. Post-test p-values: *p < 0.01 vs Control; #p < 0.01 vs CKD, †p < 0.01 vs PF, §p < 0.01 vs PF/CKD