Blood Pressure (mmHg) | BUN (mg/dL) | Serum Creatinine (mg/dL) | |||||||
---|---|---|---|---|---|---|---|---|---|
Day 0 | Day 15 | Day 30 | Day 0 | Day 15 | Day 30 | Day 0 | Day 15 | Day 30 | |
Control | 120 ± 4 | 126 ± 4 | 123 ± 3 | 17 ± 2 | 24 ± 2 | 21 ± 3 | 0.37 ± 0.03 | 0.36 ± 0.06 | 0.3 ± 0.01 |
CKD | 128 ± 2 | 162 ± 4* | 175 ± 2* | 15 ± 1 | 78 ± 6* | 134 ± 12* | 0.40 ± 0.04 | 0.70 ± 0.08* | 1.81 ± 0.15* |
PF | 124 ± 1 | 123 ± 1# | 135 ± 3# | 18 ± 2 | 18 ± 1# | 17 ± 1# | 0.29 ± 0.04 | 0.33 ± 0.04# | 0.37 ± 0.05# |
PF/CKD | 126 ± 3 | 180 ± 9*† | 169 ± 4*† | 16 ± 1 | 80 ± 10*† | 124 ± 17*† | 0.33 ± 0.02 | 1.05 ± 0.12*#† | 2.12 ± 0.2*† |
PF/CKD + TAM | 128 ± 2 | 176 ± 5*† | 166 ± 3*† | 16 ± 2 | 59 ± 5*† | 155 ± 12*† | 0.32 ± 0.03 | 0.84 ± 0.1*† | 1.72 ± 0.15*† |
PF/CKD + rBMP7 | 129 ± 3 | 175 ± 5*† | 180 ± 8*† | 20 ± 1 | 82 ± 11*† | 120 ± 9*† | 0.38 ± 0.05 | 1.20 ± 0.15*#† | 1.71 ± 0.12*† |