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Table 1 Comparative analysis of blood pressure, blood urea nitrogen (BUN) and serum creatinine levels in the different groups

From: Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

  Blood Pressure (mmHg) BUN (mg/dL) Serum Creatinine (mg/dL)
Day 0 Day 15 Day 30 Day 0 Day 15 Day 30 Day 0 Day 15 Day 30
Control 120 ± 4 126 ± 4 123 ± 3 17 ± 2 24 ± 2 21 ± 3 0.37 ± 0.03 0.36 ± 0.06 0.3 ± 0.01
CKD 128 ± 2 162 ± 4* 175 ± 2* 15 ± 1 78 ± 6* 134 ± 12* 0.40 ± 0.04 0.70 ± 0.08* 1.81 ± 0.15*
PF 124 ± 1 123 ± 1# 135 ± 3# 18 ± 2 18 ± 1# 17 ± 1# 0.29 ± 0.04 0.33 ± 0.04# 0.37 ± 0.05#
PF/CKD 126 ± 3 180 ± 9*† 169 ± 4*† 16 ± 1 80 ± 10*† 124 ± 17*† 0.33 ± 0.02 1.05 ± 0.12*#† 2.12 ± 0.2*†
PF/CKD + TAM 128 ± 2 176 ± 5*† 166 ± 3*† 16 ± 2 59 ± 5*† 155 ± 12*† 0.32 ± 0.03 0.84 ± 0.1*† 1.72 ± 0.15*†
PF/CKD + rBMP7 129 ± 3 175 ± 5*† 180 ± 8*† 20 ± 1 82 ± 11*† 120 ± 9*† 0.38 ± 0.05 1.20 ± 0.15*#† 1.71 ± 0.12*†
  1. Data are expressed as mean ± SEM
  2. *p < 0.001 vs Control
  3. #p < 0.01 vs CKD
  4. p < 0.01vs PF