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Table 1 Comparative analysis of blood pressure, blood urea nitrogen (BUN) and serum creatinine levels in the different groups

From: Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

 

Blood Pressure (mmHg)

BUN (mg/dL)

Serum Creatinine (mg/dL)

Day 0

Day 15

Day 30

Day 0

Day 15

Day 30

Day 0

Day 15

Day 30

Control

120 ± 4

126 ± 4

123 ± 3

17 ± 2

24 ± 2

21 ± 3

0.37 ± 0.03

0.36 ± 0.06

0.3 ± 0.01

CKD

128 ± 2

162 ± 4*

175 ± 2*

15 ± 1

78 ± 6*

134 ± 12*

0.40 ± 0.04

0.70 ± 0.08*

1.81 ± 0.15*

PF

124 ± 1

123 ± 1#

135 ± 3#

18 ± 2

18 ± 1#

17 ± 1#

0.29 ± 0.04

0.33 ± 0.04#

0.37 ± 0.05#

PF/CKD

126 ± 3

180 ± 9*†

169 ± 4*†

16 ± 1

80 ± 10*†

124 ± 17*†

0.33 ± 0.02

1.05 ± 0.12*#†

2.12 ± 0.2*†

PF/CKD + TAM

128 ± 2

176 ± 5*†

166 ± 3*†

16 ± 2

59 ± 5*†

155 ± 12*†

0.32 ± 0.03

0.84 ± 0.1*†

1.72 ± 0.15*†

PF/CKD + rBMP7

129 ± 3

175 ± 5*†

180 ± 8*†

20 ± 1

82 ± 11*†

120 ± 9*†

0.38 ± 0.05

1.20 ± 0.15*#†

1.71 ± 0.12*†

  1. Data are expressed as mean ± SEM
  2. *p < 0.001 vs Control
  3. #p < 0.01 vs CKD
  4. p < 0.01vs PF