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Fig. 3 | Molecular Medicine

Fig. 3

From: An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

Fig. 3

The 28-gene signature is independent of tumor, node and metastasis (TNM) stage. a Receiver operating characteristic analysis is used to assess the predictive performance of the signature and TNM stage. For glioma patients, area under the curves (AUCs) are compared between histological subtypes. b Kaplan-Meier analyses of patients stratified by tumor stage or, in the case of glioma, by histological subtype and the 28-gene signature. For histological subtypes of glioma, log-rank tests are used to compare patients within the 1st and 4th survival quartiles. For the other cancers, patients are first stratified according to TNM stage followed by median-stratification into low- and high-score groups using the 28-gene signature. P values are obtained from log-rank tests

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