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Fig. 4 | Molecular Medicine

Fig. 4

From: Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2

Fig. 4

CC16 does not markedly influence phagocytosis in isolated PMNL. a Phagocytosis of PMNL after their incubation with IL-8 or sera samples from severely injured trauma patients. Patients were grouped to no P group without pneumonia or P group with pneumonia. Samples were obtained at admission to emergency department (ED) and one (Sadeghi-Bazargani et al. 2018) day prior to pneumonia. Samples from the equal post-injury days in the corresponding no P group were used. b Phagocytosis in CD16+ granulocytes after incubation with CC16 and neutralization of CXCR1 (CXCR1-ab), CXCR2 (CXCR2-ab) as well the corresponding isotype control antibodies (ctrl-ab), respectively. c Phagocytosis of immature CD16dimCD62Lbright, (d) mature CD16brightCD62Lbright and (e) immunesuppressive CD16brightCD62Ldim granulocytes. Data are represented as mean ± SEM

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