Fig. 5

CC16-reduced apoptosis is not markedly changed by the blockade of chemokine receptors. a Apoptosis of PMNL after their incubation with IL-8 or sera samples from severely injured trauma patients. Patients were grouped to no P group without pneumonia or P group with pneumonia. Samples were obtained at admission to emergency department (ED) and one (Sadeghi-Bazargani et al. 2018) day prior to pneumonia. Samples from the equal post-injury days in the corresponding no P group were used. b Apoptosis in CD16⁺ granulocytes after incubation with CC16 and neutralization of CXCR1 (CXCR1-ab), CXCR2 (CXCR2-ab) as well the corresponding isotype control antibodies (ctrl-ab), respectively. c Apoptosis of immature CD16^dimCD62L^bright, (d) mature CD16^brightCD62L^bright and (e) immunesuppressive CD16^brightCD62L^dim granulocytes. Data are represented as mean ± SEM. p < 0.05: *: vs. ctrl