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Table 3 The Association between Genotypes and Thyroid Hormone Parameters in the Studied Population

From: Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid

 

SNPs

T4

Me (Q1- Q3)

TSH

Me (Q1- Q3)

anti-TPO

Me (Q1- Q3)

Exp1

rs1048943 AA

AG + GG

11.6 (10.7–12.5)

2.0 (1.3–3.0)

0.4 (0.1–4.3)

rs4646421 AA

AG + GG

11.7 (10.8–12.5)*

2.0 (1.3–3.0)

0.4 (0.1–3.5)

rs2070676 CC

CG + GG

11.7 (10.8–12.5)

2.0 (1.3–3.0)

0.4 (0.1–6.8)

rs3813867 CC

CG + GG

11.7 (10.8–12.5)

1.9 (1.3–2.9)

0.4 (0.1–3.5)

rs1695 AA

AG + GG

11.7 (10.8–12.5)

2.0 (1.3–3.0)

0.4 (0.1–5.1)

Exp2

rs1048943 AA

AG + GG

12.2 (11.5–13.1)

1.8 (1.3–2.8)

0.3 (0.2–0.9)

rs4646421 AA

AG + GG

12.3 (11.5–13.2)

1.6 (1.1–2.8)

0.3 (0.2–0.9)

rs2070676 CC

CG + GG

12.3 (11.5–13.2)

1.7 (1.1–2.8)

0.4 (0.2–0.9)

rs3813867 CC

CG + GG

12.2 (11.5–13.1)

1.6 (1.1–2.8)

0.3 (0.2–0.8)

rs1695 AA

AG + GG

12.3 (11.6–13.2)

1.8 (1.3–2.9)

0.3 (0.2–0.8)

Unexp

rs1048943 AA

AG + GG

12.0 (11.3–13.2)

1.7 (1.2–2.9)

0.3 (0.2–0.9)

rs4646421 AA

AG + GG

12.0 (11.1–13.0)

1.7 (1.2–2.9)

0.3 (0.2–1.3)

rs2070676 CC

CG + GG

12.2 (11.3–13.3)

2.0 (1.0–3.0)

0.4 (0.2–0.9)

rs3813867 CC

CG + GG

12.0 (11.3–13.1)

1.7 (1.2–2.9)

0.3 (0.2–1.3)

rs1695 AA

AG + GG

12.2 (11.3–13.3)

1.3 (1.0–2.0)

0.3 (0.2–0.3)

  1. * p < 0.05