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Fig. 4 | Molecular Medicine

Fig. 4

From: Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol

Fig. 4

rhMFG-E8 ameliorates acute lung injury in CLP after acute alcohol exposure. While the lungs of (a) sham rats displayed a normal histological architecture, those of (b) CLP rats treated with vehicle had alveolar septal thickening with neutrophil infiltration and hyaline deposits. The lungs of (c) CLP rats treated with rhMFG-E8, however, had less severe histological lung injury. Representative images of tissue sections with H&E staining: original magnification: 200×. Prior to CLP, all rats were exposed to acute alcohol intoxication; n = 10–14 for sham and n = 9 for other experimental groups

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