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Table 1 Patient’s demographic and clinical characteristics

From: Comparison of blood lipid profile/thyroid function markers between unipolar and bipolar depressed patients and in depressed patients with anhedonia or suicidal thoughts

 P
ParametersControl (n = 89)Bipolar depression (n = 92)Unipolar depression (n = 195)Total (n = 376)OverallBipolar depression vs. Unipolar depression
Gender0.002< 0.001
 Male25 (28.09)42 (45.65)49 (25.13)116 (30.85)  
 Female64 (71.91)50 (54.35)146 (74.87)260 (69.15)  
Age, years47.34 ± 13.0524.76 ± 12.75*44.10 ± 13.9440.13 ± 16.08< 0.001< 0.001
BMI, kg/m221.88 ± 3.1421.38 ± 4.1321.87 ± 2.9221.76 ± 3.300.4740.249
SBP, mmHg121.82 ± 16.08118.36 ± 13.00122.69 ± 16.68121.43 ± 15.770.0980.033
DBP, mmHg76.36 ± 10.2773.91 ± 11.4176.47 ± 10.9975.82 ± 10.960.1680.070
Biochemical parameters
 Glucose4.86 ± 0.584.91 ± 1.145.11 ± 1.365.00 ± 1.170.1710.184
 Triglycerides1.29 ± 0.601.05 ± 0.631.46 ± 1.211.32 ± 0.990.0040.001
 Cholesterol4.65 ± 0.874.27 ± 0.98*4.75 ± 1.064.61 ± 1.02< 0.001< 0.001
 HDL1.17 ± 0.281.18 ± 0.291.21 ± 0.301.19 ± 0.290.5080.400
 LDL2.89 ± 0.752.59 ± 0.78*2.90 ± 0.842.82 ± 0.810.0080.003
 VLDL0.60 ± 0.230.50 ± 0.27*0.64 ± 0.350.60 ± 0.310.002< 0.001
 Prolactin33.26 ± 29.6551.20 ± 63.75*38.73 ± 35.9540.67 ± 44.080.0210.029
 T47.62 ± 1.557.04 ± 1.69*7.28 ± 1.587.30 ± 1.610.0710.266
 FT41.12 ± 0.181.19 ± 0.21*1.17 ± 0.191.16 ± 0.190.0480.293
 T30.93 ± 0.190.94 ± 0.200.88 ± 0.18*0.91 ± 0.190.0220.017
 FT33.03 ± 0.403.28 ± 0.49*2.96 ± 0.403.06 ± 0.45< 0.001< 0.001
 TSH1.98 ± 1.631.99 ± 1.472.23 ± 3.472.11 ± 2.730.6980.493
 Cortisol15.50 ± 6.3917.11 ± 8.0917.68 ± 7.78*17.02 ± 7.590.1040.562
 Insulin resistance1.23 ± 0.790.99 ± 0.771.40 ± 1.611.26 ± 1.290.0430.012
Psychological index
 Anhedonia< 0.0010.003
  No62 (72.94)34 (38.20)40 (21.28)136 (37.57)  
  Yes23 (27.06)55 (61.80)148 (78.72)226 (62.43)  
 Suicidal thoughts< 0.0010.143
  No78 (91.76)51 (57.30)90 (47.87)219 (60.50)  
  Yes7 (8.24)38 (42.70)98 (52.13)143 (39.50)  
  1. *, P < 0.05 compared to control group in post-hoc comparisons
  2. HDL high-density lipoprotein cholesterol; LDL low-density lipoprotein cholesterol, VLDL very low-density lipoprotein cholesterol; T3 triiodothyronine; FT3 free T3; FT4, free T4; TSH thyroid-stimulating hormone