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Table 1 Patient’s demographic and clinical characteristics

From: Comparison of blood lipid profile/thyroid function markers between unipolar and bipolar depressed patients and in depressed patients with anhedonia or suicidal thoughts

 

P

Parameters

Control (n = 89)

Bipolar depression (n = 92)

Unipolar depression (n = 195)

Total (n = 376)

Overall

Bipolar depression vs. Unipolar depression

Gender

0.002

< 0.001

 Male

25 (28.09)

42 (45.65)

49 (25.13)

116 (30.85)

  

 Female

64 (71.91)

50 (54.35)

146 (74.87)

260 (69.15)

  

Age, years

47.34 ± 13.05

24.76 ± 12.75*

44.10 ± 13.94

40.13 ± 16.08

< 0.001

< 0.001

BMI, kg/m2

21.88 ± 3.14

21.38 ± 4.13

21.87 ± 2.92

21.76 ± 3.30

0.474

0.249

SBP, mmHg

121.82 ± 16.08

118.36 ± 13.00

122.69 ± 16.68

121.43 ± 15.77

0.098

0.033

DBP, mmHg

76.36 ± 10.27

73.91 ± 11.41

76.47 ± 10.99

75.82 ± 10.96

0.168

0.070

Biochemical parameters

 Glucose

4.86 ± 0.58

4.91 ± 1.14

5.11 ± 1.36

5.00 ± 1.17

0.171

0.184

 Triglycerides

1.29 ± 0.60

1.05 ± 0.63

1.46 ± 1.21

1.32 ± 0.99

0.004

0.001

 Cholesterol

4.65 ± 0.87

4.27 ± 0.98*

4.75 ± 1.06

4.61 ± 1.02

< 0.001

< 0.001

 HDL

1.17 ± 0.28

1.18 ± 0.29

1.21 ± 0.30

1.19 ± 0.29

0.508

0.400

 LDL

2.89 ± 0.75

2.59 ± 0.78*

2.90 ± 0.84

2.82 ± 0.81

0.008

0.003

 VLDL

0.60 ± 0.23

0.50 ± 0.27*

0.64 ± 0.35

0.60 ± 0.31

0.002

< 0.001

 Prolactin

33.26 ± 29.65

51.20 ± 63.75*

38.73 ± 35.95

40.67 ± 44.08

0.021

0.029

 T4

7.62 ± 1.55

7.04 ± 1.69*

7.28 ± 1.58

7.30 ± 1.61

0.071

0.266

 FT4

1.12 ± 0.18

1.19 ± 0.21*

1.17 ± 0.19

1.16 ± 0.19

0.048

0.293

 T3

0.93 ± 0.19

0.94 ± 0.20

0.88 ± 0.18*

0.91 ± 0.19

0.022

0.017

 FT3

3.03 ± 0.40

3.28 ± 0.49*

2.96 ± 0.40

3.06 ± 0.45

< 0.001

< 0.001

 TSH

1.98 ± 1.63

1.99 ± 1.47

2.23 ± 3.47

2.11 ± 2.73

0.698

0.493

 Cortisol

15.50 ± 6.39

17.11 ± 8.09

17.68 ± 7.78*

17.02 ± 7.59

0.104

0.562

 Insulin resistance

1.23 ± 0.79

0.99 ± 0.77

1.40 ± 1.61

1.26 ± 1.29

0.043

0.012

Psychological index

 Anhedonia

< 0.001

0.003

  No

62 (72.94)

34 (38.20)

40 (21.28)

136 (37.57)

  

  Yes

23 (27.06)

55 (61.80)

148 (78.72)

226 (62.43)

  

 Suicidal thoughts

< 0.001

0.143

  No

78 (91.76)

51 (57.30)

90 (47.87)

219 (60.50)

  

  Yes

7 (8.24)

38 (42.70)

98 (52.13)

143 (39.50)

  
  1. *, P < 0.05 compared to control group in post-hoc comparisons
  2. HDL high-density lipoprotein cholesterol; LDL low-density lipoprotein cholesterol, VLDL very low-density lipoprotein cholesterol; T3 triiodothyronine; FT3 free T3; FT4, free T4; TSH thyroid-stimulating hormone