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Table 3 Logistic regression and ROC analysis results

From: Comparison of blood lipid profile/thyroid function markers between unipolar and bipolar depressed patients and in depressed patients with anhedonia or suicidal thoughts

 Logistic regression
(Crude)
Logistic regression
(Adjusted d)
ROC analysis
ParametersOR (95% CI)POR (95% CI)PAUC (95% CI)P
Bipolar depression (as reference) vs. Unipolar depression a
 Gender
  Maleref.ref.
  Female2.50 (1.48–4.22)< 0.0011.48 (0.75–2.91)0.260
 Age, year1.10 (1.08–1.13)< 0.0011.10 (1.07–1.13)< 0.001
 SBP, mmHg1.02 (1.00–1.04)0.0331.00 (0.97–1.02)0.8240.551 (0.479–0.623)0.177
 Triglycerides1.82 (1.21–2.73)0.0041.28 (0.84–1.95)0.2490.620 (0.550–0.689)0.001
 Cholesterol1.60 (1.23–2.09)< 0.0011.31 (0.28–6.05)0.7320.633 (0.563–0.703)< 0.001
 LDL1.64 (1.17–2.29)0.0040.95 (0.62–1.45)0.7970.611 (0.540–0.682)0.003
 VLDL4.72 (1.85–12.05)0.0011.40 (0.30–6.47)0.6660.626 (0.557–0.696)< 0.001
 Prolactin0.99 (0.99–1.00)0.0600.99 (0.99–1.00)0.0920.546 (0.470–0.622)0.238
 T30.19 (0.05–0.76)0.0190.62 (0.11–3.36)0.5770.598 (0.522–0.675)0.012
 FT30.19 (0.10–0.37)< 0.0010.73 (0.32–1.66)0.4530.685 (0.613–0.758)< 0.001
 Insulin resistance1.41 (1.04–1.92)0.0280.51 (0.18–1.47)0.2140.588 (0.517–0.659)0.019
Anhedonia b
 LDL0.72 (0.52–1.00)0.0490.64 (0.45–0.91)0.0130.560 (0.482–0.638)0.129
Suicidal thoughts c
 Cholesterol1.28 (1.02–1.62)0.0371.30 (1.01–1.67)0.0430.589 (0.522–0.657)0.011
 HDL4.71 (1.97–11.27)< 0.0013.81 (1.55–9.33)0.0030.636 (0.571–0.702)< 0.001
  1. adependent variable was diagnosis, including only bipolar depression and unipolar depression patients where bipolar depression as compared reference
  2. b dependent variable was anhedonia (no or yes), ‘no’ as reference
  3. c dependent variable was Suicidal thoughts (no or yes), ‘no’ as reference
  4. d Depression model was adjusted with patient’s age, gender, triglyceridess, HDL and LDL cholesterol; anhedonia and suicidal thoughts models was adjusted with patient’s age and gender
  5. HDL high-density lipoprotein cholesterol; LDL low-density lipoprotein cholesterol, VLDL very low-density lipoprotein cholesterol; T3 triiodothyronine; FT3, free T3; FT4, free T4; TSH thyroid-stimulating hormone