Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment

Table 1 Left ventricular echocardiographic measurements

	Sham	MI + Veh	MI + T3
Heart Rate (bpm)	300 ± 31	304 ± 26	348 ± 77
Ejection Fraction (%)	82 ± 4	43 ± 8*	50 ± 5*#
Left Atrial Diameter (mm)	3.70 ± 0.49	5.21 ± 1.22*	4.68 ± 1.69
LV End Systolic Volume (cm³)	0.15 ± 0.05	1.42 ± 0.39*	1.17 ± 0.36*
LV End Diastolic Volume (cm³)	0.83 ± 0.18	2.44 ± 0.38*	2.32 ± 0.63*
Anterior wall thickness systole (mm)	2.00 ± 0.22	0.84 ± 0.17*	1.12 ± 0.33*#
Anterior wall thickness diastole (mm)	1.16 ± 0.07	0.76 ± 0.17*	0.88 ± 0.19*
Posterior wall thickness systole (mm)	2.08 ± 0.19	2.05 ± 0.13	2.11 ± 0.11
Posterior wall thickness diastole (mm)	1.15 ± 0.06	1.17 ± 0.05	1.20 ± 0.07

Values are mean ± SD. MI, myocardial infarction; Veh, vehicle; T3, triiodothyronine. Sham, n = 11; MI + Veh, n = 11; MI + T3, n = 10. One-way ANOVA, post-hoc Tukey’s multiple group comparisons. *p < 0.05 vs sham, #p < 0.05 vs MI + Veh

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