Skip to main content

Table 1 Summary of gene level differential expression analysis in RPE samples in two different conditions (Prpf31A216P/+ vs WT mice). Default filter criteria, fold change < − 2 or > 2 and ANOVA p-value < 0.05

From: Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins

Type of genesNumber of genes evaluated (%)Number of genes differentially expressed (%)Number of genes up-regulated (%)Number of genes down-regulated (%)
Non-coding36,703 (55.7)562 (0.9)485 (47.0)77 (7.5)
Complex15,644 (23.7)280 (0.4)264 (25.6)16 (1.5)
Coding10,692 (16.2)151 (0.2)134 (12.9)17 (1.6)
Pseudogene2711 (4.1)40 (0.1)39 (3.8)1 (0.1)
Ribosomal155 (0.2)0 (0.0)0 (0.0)0 (0.0)
Unassigned51(0.1)0 (0.0)0 (0.0)0 (0.0)
Total65,956 (100.0)1033 (1.6)922 (89.3)111 (10.7)
  1. MTA 1.0, genome version mm10