Skip to main content

Table 2 Summary of alternative splicing analysis in RPE samples in two different conditions (Prpf31A216P/+ vs WT mice). Default filter criteria, splicing index < −2 or > 2 and ANOVA p-value < 0.05

From: Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins

Type of genesNumber of genes evaluated (%)Number of genes expressed in both conditions (%)Genes with at least one differentially expressed PSR or junction to indicate alternative splining (%)
Non-coding36,581 (55.6)33,587 (51.1)929 (1.5)
Complex15,644 (23.8)15,056 (22.9)4344 (7.1)
Coding10,628 (16.2)9450 (14.4)1381 (2.3)
Pseudogene2711 (4.1)2601 (3.9)29 (0.1)
Ribosomal155 (0.2)155 (0.3)16 (0.0)
Unassigned51(0.1)22 (0.0)1 (0.0)
Total65,770 (100.0)60,871 (92.6)6700 (11.0)
  1. MTA 1.0, genome version mm10. PSR probe selection region