Table 2 Summary of alternative splicing analysis in RPE samples in two different conditions (Prpf31A216P/+ vs WT mice). Default filter criteria, splicing index < −2 or > 2 and ANOVA p-value < 0.05
Type of genes | Number of genes evaluated (%) | Number of genes expressed in both conditions (%) | Genes with at least one differentially expressed PSR or junction to indicate alternative splining (%) |
|---|---|---|---|
Non-coding | 36,581 (55.6) | 33,587 (51.1) | 929 (1.5) |
Complex | 15,644 (23.8) | 15,056 (22.9) | 4344 (7.1) |
Coding | 10,628 (16.2) | 9450 (14.4) | 1381 (2.3) |
Pseudogene | 2711 (4.1) | 2601 (3.9) | 29 (0.1) |
Ribosomal | 155 (0.2) | 155 (0.3) | 16 (0.0) |
Unassigned | 51(0.1) | 22 (0.0) | 1 (0.0) |
Total | 65,770 (100.0) | 60,871 (92.6) | 6700 (11.0) |