Fig. 3
Cardioprotective effects by SDF-1α secreted from S-GECS in hypoxic injury. a The effect of S-GECS CM on early and late apoptosis of CoCl2-treated cardiomyoblasts. b Changes in the proportion of early apoptotic (AV+/PI-) cardiomyoblasts during CoCl2-induced hypoxic injury after S-GECS CM treatment, each in triplicate. *p < 0.05. c Western blot analysis of CXCR4 expression in H9c2 cardiomyoblasts treated with CoCl2 for 24 h, each in quintuplicate. *p < 0.05. d The effect of S-GECS CM and gene silencing via CXCR4 siRNA CM on early and late apopotosis of cardiomyoblasts with and without CoCl2 treatment. e Comparisons of the proportion of early apoptotic (AV+/PI-) cardiomyoblasts with and without CXCR4 siRNA before and after S-GECS CM treatment, each in triplicate. *p < 0.05. f Western blot of Akt signaling with and without CoCl2 and S-GECS CM treatment, each in triplicate. *p < 0.05. g Western blot of Erk signaling with and without CoCl2 and S-GECS CM treatment, each in triplicate. *p < 0.05. Data represent the mean ± SD