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Fig. 4 | Molecular Medicine

Fig. 4

From: Enhanced expression of miR-21 and miR-150 is a feature of anti-mitochondrial antibody-negative primary biliary cholangitis

Fig. 4

The expressions of miR-21, miR-150 and their downstream target genes in peripheral blood mononuclear cells (PBMCs). MiR-21 expression was increased in PBMCs of patients with PBC in comparison to controls (a). The expression of RASGRP1 gene (b) and DNMT1(c) mRNA and protein levels were reduced in PBMCs of PBC patients. MicroRNA 150 expression was unchanged (d),whereas cMyb mRNA and protein levels were significantly decreased in PBMCs of PBC patients (e). Bars indicate the mean ± SEM

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Molecular Medicine

ISSN: 1528-3658