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Table 1 Characteristics of the three study populations

From: HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material

CharacteristicsSample Storage patients (n = 10)Serum vs. Plasma patients (n = 5)Arterial vs. Venous patients (n = 6)
Demographics
 Sex (male: female)7: 33: 26: 0
 Age (years)48 (29–68; 19–78); 1054 (30–55; 23–55); 535 (19–52; 17–57); 6
 Pre-injury ASA PS (ASA I: II: III)5: 3: 23: 1: 15: 0: 1
Injuries
 Mechanism of injury (blunt: penetrating)10: 04: 15: 1
 NISS34 (22–43; 12–75); 1041 (22–53; 9–57); 541 (7–59; 1–66); 6
 ISS28 (20–32; 5–48); 1024 (15–46; 9–57); 536 (4–49; 1–50); 6
 Admission BE (mmol/L)−4.1 (− 7.3 – − 1.0; − 8.3 – 0.1); 10−3.4 (− 5.6 – − 2.0; − 6.2 – − 1.6); 4−2.3 (− 6.2–0.3; − 8.7 – 3.7); 6
HMGB1 analyses
 Admission HMGB1 (ng/mL)a6.57 (3.01–29.9; 1.68–155); 1050.8 (1.88–91.2; 1.54–97.9); 513.2 (8.62–17.7; 7.31–20.4); 6
 Time from injury to first sample (hours)b3:07 (1:03–5:44; 0:39–7:26); 90:45 (0:31–2:41; 0:29–4:06); 51:41 (0:49–2:49; 0:17–3:50); 6
Hospital treatment
 ICU length of stay (days)6 (2–11; 1–17); 107 (3–9; 2–10); 56 (2–11; 2–12); 6
 Ventilator treatment (y: n)5: 52: 35: 1
Outcome
 Dead at 30 days (y: n)1: 91: 41: 5
 Ventilator-free days29 (11–30; 0–30); 1030 (0–30; 0–30); 523 (17–29; 0–30); 6
  1. Numbers are given as median (quartiles; range) and number of patients if not otherwise specified. NISS New Injury Severity Score, ISS Injury Severity Score, BE Base Excess, ICU intensive care unit, Ventilator-free days, days alive and off ventilator during the first 30 days after trauma. aFor “Arterial vs. Venous” group, as median concentration from first arterial sample. bTime from injury missing for one patient in “Sample Storage” group