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Table 3 Causal estimates for the association between IS and AF and mediators

From: Exploring the causal pathway from ischemic stroke to atrial fibrillation: a network Mendelian randomization study

Exposure

Outcome

Causal estimate

Num of IVs

R2

Beta/OR

95% CI

PValue

Power

IS

AF

103

6.1%

1.05

1.02–1.07

1.3 × 10−5

0.84

IS

DBP

103

6.1%

0.02

0.001–0.034

2.9 × 10−2

–

DBP

AF

91

1.5%

1.18

1.03–1.35

1.2 × 10−2

1

IS

SBP

103

6.1%

0.02

0.006–0.034

3.1 × 10−3

–

SBP

AF

80

1.7%

1.18

1.01–1.38

4.0 × 10−2

1

DBP

IS

91

1.5%

1.65

1.27–2.14

1.7 × 10−4

1

SBP

IS

80

1.7%

1.48

1.17–1.87

9.3 × 10−4

0.99

AF

IS

103

1.1%

1.18

1.08–1.28

1.3 × 10−4

1