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Fig. 6 | Molecular Medicine

Fig. 6

From: NGF (−198C > T, Ala35Val) and p75NTR (Ser205Leu) gene mutations are associated with liver function in different histopathological profiles of the patients with chronic viral hepatitis in the Brazilian Amazon

Fig. 6

Association of liver function with NGF haplotypes according to hepatic fibrosis. a Viral load was higher in patients with the haplotype containing the Ala+/+ variant in all stages of fibrosis. b and c The level of ALT and AST was lower in patients with the haplotype containing the Ala+/+ variant in all fibrosis stages. d For GGT, this trend was observed only in the F0-F1 stage. e Heatmap graph showing normalized data groupings. Heterozygous: ArgValAlaAla - ArgValValAla. Other haplotypes: ArgValAlaAla, ArgMetAlaAla, ArgValAlaAla, ArgValValAla, ArgMetValAla, ArgMetValAla, ArgValAlaAla, and ArgValAlaAla

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Molecular Medicine

ISSN: 1528-3658