Identification of biomarkers in common chronic lung diseases by co-expression networks and drug-target interactions analysis

Table 3 The Final Result of MM-GS and Disease-associated Genes Analyses for Identifying the Most Important Modules in COPD, IPF, and Asthma after Second and Third Filters

Disease	Module	No. Genes	MM-GS		Disease-associated Genes
Disease	Module	No. Genes	Correlation	P-value	Count	P-value
asthma	Skyblue	18	−0.66	0.0029	4	0.01
	Stellblue	16	0.5	0.049	2	0.37
	Darkgreen	29	0.44	0.017	0	0.17
	Lightyellow	101	0.26	0.0086	11	0.11
IPF	Blue	593	0.86	8E − 175	24	0.10
	Lightgreen	25	0.81	9.3E − 07	3	0.23
	Yellow	329	0.89	1.5E − 113	38	6E − 04
	Purple	51	0.87	1.2E − 16	5	0.28
	Red	129	0.85	3.7E − 37	4	0.20
	brown	508	0.88	1E − 165	24	0.34
	Salmon	37	0.61	6.1E − 05	3	0.59
	Green	202	0.84	5.2E − 55	11	0.81
	Black	121	0.68	9.7E − 18	19	1E − 04
	Pink	98	0.76	1.1E − 19	3	0.26
	lightyellow	25	0.87	1.6E − 08	1	0.70
COPD	Blue	678	0.85	2.4E − 190	47	0.08
	Pink	194	0.63	7.5E − 23	8	0.59
	Red	218	0.28	2.7E − 05	7	0.25
	Purple	125	0.67	1.3E − 17	7	0.35
	Turquoise	949	0.37	3.7E − 32	36	0.15
	Tan	78	0.63	6.4E − 10	7	0.15
	Brown	397	0.53	3.9E − 30	47	1E − 04
	Yellow	252	0.52	7.4E − 19	12	0.85
	Black	451	0.39	7.8E − 18	23	3E − 03
	Cyan	45	0.4	0.0065	4	0.27
	Grey60	83	0.43	5E − 05	10	0.01
	Green yellow	81	0.22	0.048	1	0.13
	Midnight blue	33	0.38	0.029	5	0.01
	Royal blue	12	0.58	0.048	0	0.45

ISSN: 1528-3658