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Table 3 TFAP2D immunostaining and Ki67 labeling index

From: Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion

ki67

TFAP2D

n=

Ki67 Li (mean)

standard error of the mean

all p < 0.0001

negative

1376

1.89

±

0.07

positive

4328

3.08

±

0.04

Gleason ≤3 + 3 p < 0.0001

negative

357

1.55

±

0.11

positive

808

2.51

±

0.07

Gleason 3 + 4 p < 0.0001

negative

730

1.81

±

0.09

positive

2483

2.91

±

0.05

Gleason 3 + 4 Tert.5 p < 0.0001

negative

61

2.10

±

0.32

positive

172

3.59

±

0.19

Gleason 4 + 3 p = 0.0025

negative

112

2.44

±

0.30

positive

435

3.45

±

0.15

Gleason 4 + 3 Tert.5 p < 0.0001

negative

59

2.12

±

0.49

positive

233

4.33

±

0.25

Gleason ≥4 + 4 p = 0.0504

negative

56

3.57

±

0.61

positive

194

4.94

±

0.33