Fig. 2From: Conditional deletion of HDAC4 from collagen type 2α1-expressing cells increases angiogenesis in vivoShortened growth plates and larger secondary ossification centers in Col2α1-Cre; HDAC4d/d mice. Safranin O/Fast green staining was performed on paraffin sections at days 14 and 21. a Shortened growth plates and larger secondary ossification centers were observed in the Col2α1-Cre; HDAC4d/d mice compared with the HDAC4f1/f1 mice on postnatal days 14 and 21. b Significant differences in the thicknesses of the growth plates and ratio of area of secondary ossification center to area of tibial plateau were observed between the Col2α1-Cre; HDAC4d/d and HDAC4f1/f1 groups on postnatal days 14 and 21. Data are expressed as mean ± SEM. *P < 0.05 vs. the vehicle groupBack to article page