Fig. 6
From: Down-regulated miR-495 can target programmed cell death 10 in ankylosing spondylitis
Exploring the potential role of miR-495. a Classical signaling pathway analysis. b Signaling pathways related to disease analysis. c Other signaling pathway analysis. Signaling pathways were analyzed by KEGG with a P value threshold of 0.01. d GO categories of miR-495. The -log P value came from enrichment analysis. The 39 GO categories (biological processes) were all with a P value threshold of 0.01. e Western blot of β-catenin and TGF-β1. AS1, AS2, and AS3: different patients with AS. Healthy controls were indicated as HC1, HC2, and HC3. n = 3: repeated samples in each group. P values were indicated as shown. F Western blot of β-catenin in transfected primary PBMCs. Mock: untreated group. Vector: blank vector group. Control: mutated miR-495 over-expression group. MiR-495: miR-495 over-expression group. g Western blot of TGF-β1 in transfected primary PBMCs. Mock: untreated group. Vector: blank vector group. Control: mutated miR-495 over-expression group. MiR-495: miR-495 over-expression group