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Fig. 2 | Molecular Medicine

Fig. 2

From: Neonatal hair profiling reveals a metabolic phenotype of monochorionic twins with selective intrauterine growth restriction and abnormal umbilical artery flow

Fig. 2

Schematic diagram of study design. 18 sIUGR MCDA pregnancies and 11 non-complicated MCDA pregnancies were included in this twin study. Among sIUGR pregnancies, 10 twin pairs were diagnosed with normal umbilical artery flow (type 1) and 8 twin pairs were abnormal UAF (types 2&3). Hairs were collected from each twin immediately after delivery for subsequent metabolomic profiling. Comparison 1 compares the metabolic disparity between T2&3 sIUGR-S and Control. Comparison 2 compares T2&3 sIUGR-L and Control. Comparison 3 compares T1 sIUGR-S and T2&3 sIUGR-S. Comparison 4 compares T1 sIUGR-L and T2&3 sIUGR-L. Comparison 5 examines T2&3 sIUGR-L and T2&3 sIUGR-S. Comparison 6 evaluates T1 sIUGR-L and T1 sIUGR-S. Comparison 7 examines T1 sIUGR-S and Control. Comparison 8 compares T1 sIUGR-L and Control. Abbreviations are as follows; sIUGR = Selective intrauterine growth restriction; MCDA = Monochorionic diamniotic; T1 = Normal umbilical artery flow; T2&3 = Abnormal umbilical artery flow; L = Larger twin; S = Smaller twin

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