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Fig. 2 | Molecular Medicine

Fig. 2

From: Estrogen-regulated PTTG1 promotes breast cancer progression by regulating cyclin kinase expression

Fig. 2

PTTG1 promoted the proliferation of breast cancer cells. a qPCR was employed to detect the mRNA levels of PTTG1 in the cells including MCF7 and T47D that were transfected with shPTTG1 or negative control shRNA. n = 3. After that, (b-d) Cell count (b) or MTT (c-d) assay was used to determine the cell viabilities. n = 7. Additionally, (e) cells including MCF7 and T47D were used to establish PTTG1 overexpression cell lines. qPCR was employed to detect the mRNA levels of PTTG1 in the cells. n = 3. f-h Cell count (f) or MTT (g-h) assay was used to determine the cell viabilities. n = 7. Data are represented as mean ± S.D. ***P < 0.001

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