Skip to main content
Fig. 4 | Molecular Medicine

Fig. 4

From: Estrogen-regulated PTTG1 promotes breast cancer progression by regulating cyclin kinase expression

Fig. 4

The levels of PTTG1 were associated with tamoxifen resistance of breast cancer cells. a MTT was used to determine cell viabilities of MCF7 cells that were transfected with vector or plasmids containing PTTG1 sequence. n = 6. b Cell viabilities of MCF7 or tamoxifen resistant (TamR) cells were also determined. n = 6. c-d qPCR was employed to determine the mRNA levels of PTTG1 in the MCF7 cells, TamR cells, and TamR cells that were transfected with shPTTG1 or control shRNA. n = 3. e-f MTT was used to determine the cell viabilities of TamR cells that were transfected with shPTTG1 or control shRNA and MCF7 cells that were transfected with vector or plasmids containing PTTG1 sequence. n = 6. Data were represented as mean ± S.D. ***P < 0.001

Back to article page