Fig. 5
From: Estrogen-regulated PTTG1 promotes breast cancer progression by regulating cyclin kinase expression
PTTG1 regulated the expressions of CCNA2 and CCNB2 in the breast cancer cells. a-b TCGA breast cancer dataset was used to explore the correlation between PTTG1 and genes including CCNA2 and CCNB2. c-d qPCR was employed to determine the mRNA levels of CCNA2 and CCNB2 in the PTTG1-knockdown and -overexpression cells. n = 3. e PI staining was performed and flow cytometry was used to analyze the effects of PPTG1 on the cell cycle. Data were represented as mean ± S.D. ***P < 0.001