Table 1 Clinical characteristics and biomarker measures
| Controls (n = 14) | AD (n = 19) | |
|---|---|---|
| Age (years), mean (SD) | 70.5 (4.1) | 69.7 (4.6) |
| Gender, No. (%) of males | 5 (35.7%) | 10 (52.6%) |
| Education years, mean (SD) | 13.1 (2.6) | 13.3 (2.5) |
| MMSE scale, mean (SD) | 28.6 (1.8) | 23.8 (3.9)* |
| APOEε4 carriers, No. (%) | 2 (14.3%) | 9 (47.4%)* |
| CSF MIF (ng/ml), mean (SD) | 0.158 (0.096) | 0.270 (0.168) |
| Plasma MIF (ng/ml), mean (SD) | 0.045 (0.077) | 0.113 (0.170) |
| CSF Aβ 1–42 (pg/ml), mean (SD) | 990.3 (203.9) | 522.8 (134.0)* |
| CSF tau (pg/ml), mean (SD) | 182.1 (44.4) | 738.5 (407.9)* |
| CSF p-tau181 (pg/ml), mean (SD) | 42.6 (12.4) | 93.9 (35.7)* |