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Fig. 2 | Molecular Medicine

Fig. 2

From: The protective effects of the β3 adrenergic receptor agonist BRL37344 against liver steatosis and inflammation in a rat model of high-fat diet-induced nonalcoholic fatty liver disease (NAFLD)

Fig. 2

Histological changes in the liver in the control, HFD, HFD + β3-AGO and HFD + β3-ANT groups (each group, n = 8). a The control group showed normal liver histological features, and the hepatocytes were arranged in an orderly manner. b In the HFD group, prominent hepatic steatosis, inflammation and ballooning degeneration were observed. c In the HFD + β3-AGO group, significantly improved structural changes with limited hepatic steatosis, inflammation and ballooning degeneration were observed. d The image for the HFD + β3-ANT group shows several scattered balloon cells that are much larger than the surrounding steatotic hepatocytes, in sharp contrast to the normal hepatocytes in the image in (a). The magnification is 200 ×

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