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Fig. 3 | Molecular Medicine

Fig. 3

From: The protective effects of the β3 adrenergic receptor agonist BRL37344 against liver steatosis and inflammation in a rat model of high-fat diet-induced nonalcoholic fatty liver disease (NAFLD)

Fig. 3

The β3-AR agonist BRL37344 ameliorated HFD-fed rat liver steatosis, exerting a protective effect. a Rat body weight at 0, 4, 8, and 12 weeks. b Liver weight at the 12th week in the control, HFD, HFD + β3-AGO and HFD + β3-ANT groups. c Liver index values at the 12th week in the control, HFD, HFD + β3-AGO and HFD + β3-ANT groups. d Liver homogenate TG levels (mmol/g). e Liver homogenate TC levels (mmol/g). f Liver homogenate FFA levels (μmol/g). g Oil red O was used to visualize lipid droplets in the hepatocytes. The magnification is 200×. Lipid droplets are stained light red, and nuclei are stained blue. h Quantitative analysis of lipid droplets in hepatocytes. TG: triglyceride. TC: total cholesterol. FFA: free fatty acid. *P < 0.05 vs the control group, #P < 0.05 vs the HFD group; n = 8 per group

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Molecular Medicine

ISSN: 1528-3658