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Table 3 Histopathological findings in liver tissue

From: The protective effects of the β3 adrenergic receptor agonist BRL37344 against liver steatosis and inflammation in a rat model of high-fat diet-induced nonalcoholic fatty liver disease (NAFLD)

 Control (n = 8)HFD (n = 8)HFD + β3-AGO (n = 8)HFD + β3-ANT (n = 8)
Steatosis
 Grade 08010
 Grade 1357221
 Grade 25231917
 Grade 3018630
Ballooning
 Grade 0487190
 Grade 10232918
 Grade 2018030
Inflammation
 Grade 0340120
 Grade 1146240
 Grade 20311218
 Grade 3011030
  1. Two sections of each liver specimen were observed and three views of each section were analysed. Therefore, each group had 48 views (8 rats × 2 sections × 3 views) in total. We calculated the view number distributed in grading NAFLD activity scores (NASs) according to the following categories: steatosis (0–3), lobular inflammation (0–3) and ballooning degeneration (0–2). For steatosis, lobular inflammation and ballooning degeneration, P < 0.05, HFD vs control; P < 0.05, HFD vs HFD + β3-AGO; P < 0.05, HFD vs HFD + β3-ANT