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Fig. 4 | Molecular Medicine

Fig. 4

From: An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes

Fig. 4

Clinical influences of the somatic mutations together with relevant pathways. a Clustering the LUSC patients by their expression profiles in both the significant mutated genes and other genes in the relevant pathways. b Kaplan-Meier (KM)-plot of the 10 year overall survival curves for two clusters of patients. c Enriched pathways of the top-50 important genes for stratifying the cohort into the two clusters. The gene importance was scored by random forest method

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