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Fig. 6 | Molecular Medicine

Fig. 6

From: MicroRNA-214 modulates the senescence of vascular smooth muscle cells in carotid artery stenosis

Fig. 6

MicroRNA-214-3p (miR-214) was upregulated in plasma from carotid artery stenosis patients with elevated LDL-C value. a The expression of miR-214 in plasma of CAS patients with normal LDL-C value (n = 9) and CAS patients with high LDL-C value (n = 8) were analyzed by qRT-PCR and normalized to corresponding cel miR-39 levels (Two-tailed Student’s t-test). Data are presented as the means ± SEM. Differences were analyzed by Mann-Whitney test. ** P < 0.01 (Two-tailed Student’s t-test). b Assessment of the receiver operator characteristic (ROC) curve for the predictive power of the mir-214 circulating level in patients having high LDL-C level. The area under the ROC curve (AUC) was 0.96 (p = 0 0013). The optimal cut-off point is labeled by the red solid circle

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