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Fig. 5 | Molecular Medicine

Fig. 5

From: Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in developing neurons by targeting LATS2

Fig. 5

MiR-215 attenuated propofol-induced apoptosis and oxidative stress in neonatal rat hippocampal neuron by targeting LATS2. a Western blot analysis revealed LATS2 protein level. Statistical analysis was conducted via one-way ANOVA by Tukey’s test. b Cell viability was examined using MTT assay. Statistical analysis was conducted via one-way ANOVA by Tukey’s test. c Flow cytometry analysis was used to detect apoptosis. Statistical analysis was conducted via one-way ANOVA by Tukey’s test. d Levels of ROS, LDH, MDA and SOD were analyzed in neonatal rat hippocampal neuron. Statistical analysis was conducted via one-way ANOVA by Tukey’s test. n = 3. *, p < 0.05. **, p < 0.01. #, p < 0.05. ##, p < 0.01. * vs Propofol+miR-NC + Vector. # vs Propofol+miR-215 + Vector

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Molecular Medicine

ISSN: 1528-3658