Skip to main content
Fig. 3 | Molecular Medicine

Fig. 3

From: Overexpression of RPN2 suppresses radiosensitivity of glioma cells by activating STAT3 signal transduction

Fig. 3

Abnormal expression of RPN2 leads to radioresistance in GBM cells. a U87 and A172 resistant cells transfected with control or RPN2 siRNA were treated with 5 GY radiation. The survival was analyzed by MTS assay. b The apoptosis of U87 and A172 resistant cells treated as in (a). c The expression of RPN2 and CASP3 in U87 resistant cells treated as in (a). d U87 parental cells transfected with control or RPN2 plasmids were treated with 5 GY radiation. The survival was analyzed by MTS assay. e The apoptosis of U87 parental cells treated as in (d). f The expression of RPN2 and CASP3 in U87 parental cells treated as in (d). Each experiment was performed for 3 times. *, p < 0.05; **, p < 0.01

Back to article page

Molecular Medicine

ISSN: 1528-3658