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Table 1 Characteristics of study subjects

From: Circulating fibrocytes traffic to the lung in murine acute lung injury and predict outcomes in human acute respiratory distress syndrome: a pilot study

Demographic Information ARDS
(n = 42)
Pneumonia without ARDS
(n = 12)
Healthy Controls
(n = 20)
pvalue
Age/years (median and IQR) 54 (41–63) 56 (48–70) 55 (46–62) 0.51
Sex (% male) 57 42 50 0.61
Race (%)
Caucasian 83 67 60 0.19
African American 17 33 35
Asian 0 0 5
mSOFA score at enrollment (median and IQR) 7 (6–9) 6 (3–9) 0.36
Mechanical ventilation (%) 98 33 < 0.0001
Type (% conventional) 100 100   0.99
PEEP (median and IQR) 12 (10–14) 8 (7–9)   0.01
Vt (median and IQR) 400 (350–448) 380 (345–400)   0.39
P:F ratio at enrollment 123 (99–156) 161 (156–193) 0.02
Vasopressor use (%) 67 25 0.01
Immunocompromised (%) 31 33 0.99
Cause of ARDS (%)    
Pneumonia 76  
Sepsis 10  
Aspiration 7  
Other 7  
ICU length of stay/days (median and IQR) 7 (5–10) 6 (1–12) 0.35
In-hospital mortality (%) 38 33 0.99
  1. Abbreviations: ARDS, acute respiratory distress syndrome; mSOFA, modified sequential organ failure assessment score (excluding the Glasgow coma scale component); ICU, intensive care unit; IQR, inter-quartile range; PEEP, positive end-expiratory pressure, Vt, tidal volume (in mL), P:F ratio, ratio of PaO2 to FIO2. Types of mechanical ventilation within 24 h of enrollment included conventional (volume- or pressure-controlled mode, extra-corporeal membrane oxygenation (ECMO), or high frequency oscillatory ventilation (HFOV). “Other” causes of ARDS were two cases of acute pancreatitis and one case of catastrophic antiphospholipid antibody syndrome