Table 1 Characteristics of study subjects
Demographic Information | ARDS (n = 42) | Pneumonia without ARDS (n = 12) | Healthy Controls (n = 20) | pvalue |
|---|---|---|---|---|
Age/years (median and IQR) | 54 (41–63) | 56 (48–70) | 55 (46–62) | 0.51 |
Sex (% male) | 57 | 42 | 50 | 0.61 |
Race (%) | ||||
Caucasian | 83 | 67 | 60 | 0.19 |
African American | 17 | 33 | 35 | |
Asian | 0 | 0 | 5 | |
mSOFA score at enrollment (median and IQR) | 7 (6–9) | 6 (3–9) | – | 0.36 |
Mechanical ventilation (%) | 98 | 33 | – | < 0.0001 |
Type (% conventional) | 100 | 100 | 0.99 | |
PEEP (median and IQR) | 12 (10–14) | 8 (7–9) | 0.01 | |
Vt (median and IQR) | 400 (350–448) | 380 (345–400) | 0.39 | |
P:F ratio at enrollment | 123 (99–156) | 161 (156–193) | – | 0.02 |
Vasopressor use (%) | 67 | 25 | – | 0.01 |
Immunocompromised (%) | 31 | 33 | – | 0.99 |
Cause of ARDS (%) | – | |||
Pneumonia | 76 | – | – | |
Sepsis | 10 | – | – | |
Aspiration | 7 | – | – | |
Other | 7 | – | – | |
ICU length of stay/days (median and IQR) | 7 (5–10) | 6 (1–12) | – | 0.35 |
In-hospital mortality (%) | 38 | 33 | – | 0.99 |