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Table 2 Basic characteristics and allele frequencies of the seven IL-1B SNPs

From: IL-1B rs2853550 polymorphism contributes to esophageal cancer susceptibility in Chinese Han population of Northwest China

SNP Gene Chromosome Allele Minor Allele Frequency OR (95% CI) pa
Case Control
rs2853550 IL-1B 2q13 A < G 0.117 0.088 1.38 (1.01–1.89) 0.041
rs1143643 IL-1B 2q13 C < T 0.471 0.470 1.00 (0.83–1.22) 0.949
rs3136558 IL-1B 2q13 G < A 0.397 0.374 1.10 (0.90–1.33) 0.334
rs1143630 IL-1B 2q13 T < G 0.156 0.159 0.98 (0.76–1.27) 0.861
rs1143627 IL-1B 2q13 G < A 0.453 0.479 0.91 (0.75–1.09) 0.295
rs16944 IL-1B 2q13 A < G 0.456 0.474 0.93 (0.77–1.12) 0.444
rs1143623 IL-1B 2q13 G < C 0.362 0.399 0.85 (0.70–1.04) 0.114
  1. SNP Single nucleotide polymorphism, OR Odds ratio, 95% CI 95% confidence interval
  2. pa values were calculated using χ2 test for comparison of the allele distribution frequencies among EC patients and healthy controls
  3. Bold italics indicates the SNP with statistical significance (p < 0.05)