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Table 2 Basic characteristics and allele frequencies of the seven IL-1B SNPs

From: IL-1B rs2853550 polymorphism contributes to esophageal cancer susceptibility in Chinese Han population of Northwest China

SNP

Gene

Chromosome

Allele

Minor Allele Frequency

OR (95% CI)

pa

Case

Control

rs2853550

IL-1B

2q13

A < G

0.117

0.088

1.38 (1.01–1.89)

0.041

rs1143643

IL-1B

2q13

C < T

0.471

0.470

1.00 (0.83–1.22)

0.949

rs3136558

IL-1B

2q13

G < A

0.397

0.374

1.10 (0.90–1.33)

0.334

rs1143630

IL-1B

2q13

T < G

0.156

0.159

0.98 (0.76–1.27)

0.861

rs1143627

IL-1B

2q13

G < A

0.453

0.479

0.91 (0.75–1.09)

0.295

rs16944

IL-1B

2q13

A < G

0.456

0.474

0.93 (0.77–1.12)

0.444

rs1143623

IL-1B

2q13

G < C

0.362

0.399

0.85 (0.70–1.04)

0.114

  1. SNP Single nucleotide polymorphism, OR Odds ratio, 95% CI 95% confidence interval
  2. pa values were calculated using χ2 test for comparison of the allele distribution frequencies among EC patients and healthy controls
  3. Bold italics indicates the SNP with statistical significance (p < 0.05)