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Fig. 1 | Molecular Medicine

Fig. 1

From: RETRACTED ARTICLE: WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation

Fig. 1

The expression of WRN is decreased and the methylation level of WRN is increased in the anterior lens capsule tissues of patients with ARC. Anterior lens capsule tissues were obtained from the patients with different types of ARC (cortical, nuclear and posterior subcapsular cataract). The healthy anterior lens capsule tissues from age-matched person were as control. a QRT-PCR and b WB were performed to detect the gene and protein expression of WRN in the anterior lens capsule tissues. c MSP was performed to detect the methylation level of WRN in the anterior lens capsule tissues. M: methylation; U: unmethylation. (**P < 0.01 compared with the Control group)

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