Fig. 9

Ischemia, CQ absence of caspase-1/11signaling alter oxidative metabolism in muscle stellate cells (MuSC). Seahorse™ analysis of maximal respiration, spare respiratory capacity (including %), non-mitochondrial oxygen consumption, ATP production, and coupling efficiency in MuSC harvested from tibialis anterior (TA) of nonischemic and ischemic limbs of C57Bl6/J (WT) and caspase1/11KO mice at 21 days after femoral artery ligation (FAL) treated with either PBS or CQ (50 mg/kg); * p < 0.05, **p < 0.01, ***p < 0.001