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Fig. 4 | Molecular Medicine

Fig. 4

From: Combination of TLR agonist and miR146a mimics attenuates ovalbumin-induced asthma

Fig. 4

Simultaneous administration of TLR2 agonist and miR146a mimics efficiently protect mice against OVA-induced allergic asthma. a Schematic diagram of the experimental protocol. The doses of Pam3CSK4 and miR146a mimics were 0.1 mg/kg and 1 mg/kg, respectively. b Eosinophils in CD45+ cells in BALF. c Eosinophils in BALF. d Histologic sections of lungs from each group were analyzed by H&E. Pictures show representative samples of 6 mice/group. Scale bar = 100 μm. e Histological scores for assessment of lung injury were shown. Data represent means ± SD. WT, wide type mice without OVA-induced allergic asthma. n = 6, *p < 0.05, **p < 0.005, ***p < 0.001

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