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Fig. 5 | Molecular Medicine

Fig. 5

From: Combination of TLR agonist and miR146a mimics attenuates ovalbumin-induced asthma

Fig. 5

Simultaneous administration of TLR2 agonist and miR146a mimics attenuates OVA-induced allergic asthma by increasing Th2 cytokines. The levels of OVA-specific IgE in serum (a), IL-4 (b), IL-5 (c), and IL-13 (d) in BALF. Serum and BALF were collected 24 h after the last challenge. The levels of OVA-specific IgE and these cytokines were quantified by ELISA. Data represent means ± SD. WT, wide type mice without OVA-induced allergic asthma. n = 6, *p < 0.05, **p < 0.005, ***p < 0.001

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