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Fig. 3 | Molecular Medicine

Fig. 3

From: circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signals

Fig. 3

Knockdown of circCELSR1 inhibited proliferation and promoted apoptosis via miR-598 in SKOV3 and A2780 cells. After SKOV3 and A2780 cells transfected with sh-circCELSR1, miR-598 mimics or miR-598 inhibitor, (a) Colony formation assay to detect SKOV3 and A2780 cells colony-forming ability. b The colony formation number was quantified by Image J. c The SKOV3 and A2780 cells apoptotic rate was determined by flow cytometry. d Quantitative analysis of cell apoptotic rate. All the results were shown as mean ± SD (n = 3). * p < 0.05 and ** p < 0.01

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