Fig. 3From: circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signalsKnockdown of circCELSR1 inhibited proliferation and promoted apoptosis via miR-598 in SKOV3 and A2780 cells. After SKOV3 and A2780 cells transfected with sh-circCELSR1, miR-598 mimics or miR-598 inhibitor, (a) Colony formation assay to detect SKOV3 and A2780 cells colony-forming ability. b The colony formation number was quantified by Image J. c The SKOV3 and A2780 cells apoptotic rate was determined by flow cytometry. d Quantitative analysis of cell apoptotic rate. All the results were shown as mean ± SD (n = 3). * p < 0.05 and ** p < 0.01Back to article page