Fig. 4From: circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signalsKnockdown of circCELSR1 repressed migration and invasion of ovarian cancer cells via targeting miR-598. Cell migration of SKOV3 and A2780 were measured by wound healing assays (a) and quantification of relative migration rate (b) in SKOV3 and A2780 cells transfected with sh-circCELSR1, miR-598 mimics or miR-598 inhibitor. Cell invasion of SKOV3 and A2780 were measured by transwell system mediated cell invasion assays (c) and quantification of number of invaded cells (d). All the results were shown as mean ± SD (n = 3). * p < 0.05 and ** p < 0.01Back to article page