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Fig. 4 | Molecular Medicine

Fig. 4

From: Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options

Fig. 4

Genetic fingerprints of somatic variants in matching primary and secondary tumors. The different types of SNVs/indels and CNVs and associated copy number (CN) changes identified by capSMART analysis of patient tumors are indicated by color coding. PT = primary tumor; BM = bone metastasis. Shared SNVs/indels were scored when both PT and BM had a variant allelic frequency of ≥3%, shared gene amplifications were scored when both PT and BM had a CN ≥ 4 and shared gene deletions were scored when both PT and BM had a CN ≤ 1

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Molecular Medicine

ISSN: 1528-3658