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Table 4 Diagnostic performances of serum miR-223 and APRIL to discriminate RA patients from healthy controls

From: Serum a proliferation-inducing ligand and MicroRNA-223 are associated with rheumatoid arthritis: diagnostic and prognostic implications

miRNA

AUC (95%CI)

P value

Best cutoff value

Sensitivity %

Specificity %

PPV %

NPV %

miR-223

0.85 (0.79 to 0.91)

< 0.0001

> 2.5 fold

80

95.38

94.11

83.78

APRIL

1* (1 to 1)

< 0.0001

> 4.19 ng/ml

100

100

100

100

  1. PPV Positive predictive value, NPV negative predictive value. *significant difference between AUCs, P < 0.0001. RA, n = 120; healthy controls, n = 130
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Molecular Medicine

ISSN: 1528-3658