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Fig. 2 | Molecular Medicine

Fig. 2

From: Long noncoding RNA CASC2 inhibits ox-LDL-mediated vascular smooth muscle cells proliferation and migration via the regulation of miR-532-3p/PAPD5

Fig. 2

CASC2 sponged miR-532-3p in AS patients. a The common binding sequences between CASC2 and miR-532-3p by Starbase and RegRNA or PITA database. b The luciferase activities in VSMCs co-transfected with miR-532-3p mimic and CASC2-WT or CASC2-MUT vector. c qRT-PCR for miR-532-3p expression in VSMCs with si-CASC2 or CASC2. d qRT-PCR for miR-532-3p expression in serum of AS patients and healthy people. e Pearson’s correlation between CASC2 and miR-532-3p in the serum of AS patients (r = − 0.533, P < 0.001). **P < 0.01; ***P < 0.001

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