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Fig. 4 | Molecular Medicine

Fig. 4

From: Long noncoding RNA CASC2 inhibits ox-LDL-mediated vascular smooth muscle cells proliferation and migration via the regulation of miR-532-3p/PAPD5

Fig. 4

Over-expression of miR-532-3p or silencing of PAPD5 on the lncCASC2-induced proliferation of VSMCs. a CCK-8 assay of VSMCs co-transfected with CASC2 or control, and miR-532-3p mimic or si-PAPD5. b BrdU incorporation assay of VSMCs co-transfected with CASC2 or control, and miR-532-3p mimic or si-PAPD5. c Colony formation assay of VSMCs co-transfected with CASC2 or control, and miR-532-3p mimic or si-PAPD5. d Cell apoptosis assay of VSMCs co-transfected with CASC2 or control, and miR-532-3p mimic or si-PAPD5. * vs. NC group or NC + ox-LDL group, # vs. CASC2 group. ***P < 0.001, **P < 0.01, #P < 0.05

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