Fig. 2
From: THRIL mediates endothelial progenitor cells autophagy via AKT pathway and FUS
The expression of VCAM-1/ICAM-1 and AKT signaling pathway in cells. (a) and (b) QRT-PCR results demonstrated that shTHRIL suppressed the expression of VCAM-1 and ICAM-1 and over-expression of THRIL could promote CAD progress. (c) and (d) AKT signaling pathway expressions in various transfection groups. (d) The expressions levels of ATG1 and LC3-II in various transfection groups. Normal: EPCs from healthy controls; NC: EPCs isolated from CAD patients; All the transfection experiments were performed in EPCs isolated from CAD patients. *P < 0.05, compared with NC group; #P < 0.05, compared with normal ones. The data shown represent three separate experiments performed in triplicate in each experiment (mean ± the standard deviation [SD])