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Table 4 Prevalence of haplotype frequencies in the obesity and control groups [n (frequency)]

From: The MC4R SNPs, their haplotypes and gene-environment interactions on the risk of obesity

Haplotype

Obesity

Control

χ2

P

OR (95% CI)

C-C-A

227.77 (0.133)

153.67 (0.079)

28.845

<  0.001

1.796 [1.447–2.229]

C-C-G

9.23 (0.005)

9.31 (0.005)

–

–

–

T-C-A

0.00 (0.000)

1.01 (0.001)

–

–

–

T-C-G

56.00 (0.033)

48.99 (0.025)

1.896

0.168458

1.313 [0.890–1.938]

T-T-A

38.23 (0.022)

69.32 (0.035)

5.570

0.018294

0.620 [0.416–0.925]

T-T-G

1384.77 (0.807)

1673.67 (0.856)

15.946

<  0.001

0.699 [0.586–0.834]

  1. The haplotype is combined with MC4R rs17782313-rs476828-rs12970134. Rare Hap (frequency < 3%) in both groups has been ignored in analysis